血清降钙素原、C反应蛋白与血常规联合检测在细菌感染患儿临床诊断中的价值

Value of combined detection of serum procalcitonin,C-reactive protein and routine blood in the clinical diagnosis of children with bacterial infection

目的探究分析血清降钙素原、C反应蛋白与血常规联合用于细菌感染患儿临床诊断中的价值。方法选取2019年3月—2020年6月白城市医院收治的84例感染患儿作为研究对象,根据是否为细菌感染分为研究组(细菌感染)和参照组(非细菌感染),每组各42例。所有患儿均接受血清降钙素原与C反应蛋白及血常规检测,统计分析两组血清降钙素原与C反应蛋白及血常规的检出结果与血清降钙素原检测、C反应蛋白检测、血常规检测及联合检测的准确度、灵敏度、特异度。结果研究组血清降钙素原与C反应蛋白及白细胞计数检出水平均高于参照组,血清降钙素原与C反应蛋白及血常规的阳性检出率均高于参照组,联合检测的准确度、灵敏度、特异度高于血清降钙素原检测、C反应蛋白检测及血常规检测,差异有统计学意义(P<0.05)。结论细菌感染患儿与非细菌感染患儿的血清降钙素原与C反应蛋白及白细胞计数水平存在明显差异,血清降钙素原与C反应蛋白及血常规检测能够准确对不同感染群体进行区分,联合检测的诊断价值明显高于单一检测,临床上可根据实际情况灵活选用。

Objective To explore and analyze the value of combined serum procalcitonin,C-reactive protein and blood routine in the clinical diagnosis of children with bacterial infections.Methods A total of 84 infected children admitted to Baicheng Hospital from March 2019 to June 2020 were selected as the research objects and divided into the study group(with bacterial infection)and the reference group(non-bacterial infections),with 42 cases in each group.All children received serum procalcitonin and C-reactive protein and routine blood tests.Statistical analysis of the study group and the reference group of serum procalcitonin and C The accuracy,sensitivity and specificity of the detection results of reactive protein and blood routine test and serum procalcitonin detection,C-reactive protein detection,blood routine detection and combined detection.Results The detection levels of serum procalcitonin,C-reactive protein and white blood cell counts in the study group were higher than those of the reference group,and the positive detection rates of serum procalcitonin,C-reactive protein and blood routine tests were all higher than those of the reference group.The accuracy,sensitivity,and specificity were higher than those of serum procalcitonin detection,C-reactive protein detection and blood routine detection,and the differences were statistically significant(P<0.05).Conclusion There are significant differences in the levels of serum procalcitonin,C-reactive protein and white blood cell counts between children with bacterial infections and children with non-bacterial infections.Serum procalcitonin,C-reactive protein and blood routine tests can accurately distinguish different infection groups,The diagnostic value of the combined test is significantly higher than that of a single test,and it can be flexibly selected according to the actual situation in clinical practice.