摘要
characterized by transmural eosinophilic inflammation of the bladder wall,accompanied by increased urine frequency,hematuria,dysuria,and suprapubic pain.[1]It has rarely been reported in children.The median age at diagnosis in the pediatric population is 6.5 years.There is no standard treatment for EC in childhood,and most patients receive non-steroidal anti-inflammatory agents or steroids as adjuvant therapy.121 Most cases in children are self-limiting and do not require more invasive treatments,but serious complications can occur and relapsing forms have been described.Subsequently,there may be a need for long-term monitoring with relevant blood and urine tests and imaging.13,41 Biopsy is essential for the diagnosis of EC.Currently,cystoscopy with biopsy is recommended by international guidelines.Cystoscopy biopsy is invasive,cost-intensive.If the disease is confined to the bladder submucosa,without the involvement of the mucosal layer,it is tricky to perform the cystoscopic biopsy,because the whole layer bladder biopsy is not chosen by cystoscopy biopsy.Cystoscopy biopsy is an unpleasant and costly procedure.
