根管填充环氧树脂类糊剂治疗根尖周炎的疗效及对患者炎性因子的影响

Clinical efficacy of root canal filling epoxy resin paste in treatment of periapical inflammation and its effect on inflammatory factors

目的:分析在根尖周炎患者治疗中采用根管填充环氧树脂类糊剂的疗效及对患者炎性因子的影响。方法:选取我院收治的70例根尖周炎患者作为本次研究对象,基于治疗方式的差异分为观察组与对照组,两组各有患者35例。对比两组患者的治疗效果和治疗前后患者炎性因子的变化情况。结果:治疗结束后,观察组的治疗总有效率明显优于对照组患者,组间差异明显(P<0.05);两组患者治疗后静息和咬合VAS评分对比中,观察组患者VAS评分情况明显低于对照组,组间差异明显(P<0.05),而在炎性因子方面,观察组患者的血清c反应蛋白、白介素-6、肿瘤坏死因子-α炎性因子下降水平明显高于对照组患者,组间差异明显(P<0.05)。结论:在根尖周炎患者治疗中采用根管填充环氧树脂类糊剂能够有效的改善患者的治疗效果与炎症情况,缓解患者的疼痛。

Objective:To investigate the clinical effect of root canal filling epoxy resin paste in the treatment of periapical periodontitis and its effect on inflammatory factors.Methods:Seventy cases of periapical periodontitis in our hospital were selected as the research object,and were divided into observation group and control group according to different treatment methods,35 cases in each group.The therapeutic effect and the changes of inflammatory factors before and after treatment were compared between the two groups.Results:The total effective rate of the observation group was significantly better than that of the control group,the difference was statistically significant(P<0.05).After treatment,the resting and occlusal VAS scores in the observation group were significantly lower than those in the control group,with statistical significance(P<0.05).After treatment,serum C-reactive protein,IL-6,tumor necrosis factor-α and other inflammatory factors in the observation group decreased more significantly than that in the control group,with statistical significance(P<0.05).Conclusion:The application of epoxy resin paste in the treatment of periapical periodontitis can effectively improve the inflammation,relieve the pain of patients,and has a significant effect.