睑板腺按摩联合药物治疗睑板腺功能障碍型干眼的临床疗效分析

Analysis of Clinical Curative Effect of Meibomian Gland Massage Combined with Medicine on Dry Eye with Meibomian Gland Dysfunction

目的睑板腺功能障碍型干眼患者通过按摩睑板腺和服用药物进行联合治疗,对患者的临床治疗效果进行研究分析。方法该次研究抽取该院在2018年6月—2019年6月期间收治的80例睑板腺功能障碍型干眼患者,采用随机数表法分成40例观察组和40例对照组。对照组通过单纯药物治疗,利用妥布霉素地塞米松眼膏进行涂眼治疗,观察组以对照组为基础,联合按摩睑板腺进行治疗,比较两组患者的治疗总有效率以及自觉症状评分和BUT(泪膜破裂时间),评价联合治疗的临床效果。结果观察组患者的临床治疗总有效率(95.0%)高于对照组患者(75.0%),差异有统计学意义(χ^(2)=6.275,P<0.05);两组患者的治疗前自觉症状评分差异无统计学意义(P﹥0.05),治疗后,观察组评分为(0.30±0.14)分,对照组评分为(0.78±0.23)分,差异有统计学意义(t=11.275,P<0.05);观察组患者的BUT时间低于5 s的患者有2例,5~10 s的患者有24例,超过10 s的患者有14例,对照组患者的BUT时间低于5 s的患者有10例,5~10 s的患者有22例,超过10 s的患者有8例,BUT时间低于5 s相比,差异有统计学意义(χ^(2)=6.275,P<0.05),5~10 s和超过10 s比较,差异无统计学意义(χ^(2)=0.205、2.257,P>0.05)。结论通过按摩睑板腺,服用药物,对睑板腺功能障碍型干眼患者进行治疗,治疗效果明显,有效延长泪膜破裂时间,降低自觉症状评分,临床效果显著。

Objective To study and analyze the clinical treatment effect of patients with meibomian gland dysfunction type dry eye by massaging the meibomian glands and taking drugs.Methods 80 cases selected in this study were all from the patients with meibomian gland dysfunction type dry eye admitted to the hospital from June 2018 to June 2019 as the research objects.The random number table method was used,divided into 40 of the observation group and 40 of the control group.The control group was treated with drugs alone and treated with tobramycin and dexamethasone ointment.The observation group was treated as a control group.Based on the control group,combined massage of the meibomian glands for treatment,comparing the total effective rate of treatment and the scores of symptoms and BUT(tear film rupture time)of the two groups of patients to evaluate the clinical effect of the combined treatment.Results The total effective rate of clinical treatment in the observation group(95.0%)was higher than that of the control group(75.0%),and the difference was statistically significant(χ^(2)=6.275,P<0.05);the subjective symptoms score of the two groups of patients before treatment was not statistically significant difference(P>0.05).After treatment,the observation group score was(0.30±0.14)points,and the control group score was(0.78±0.23)points,the difference was statistically significant(t=11.274,P<0.05));there were 2 patients in the observation group with BUT time less than 5 s,24 patients with 5-10 s,14 patients with more than 10 s,and control group patients with BUT time less than 5 s 10 cases,22 cases of 5-10 s patients,8 cases of more than 10 s patients,BUT time was less than 5 s,the difference was statistically significant(χ^(2)=6.275,P<0.05),5~10 s compared with more than 10 s,the difference was not statistically significant(χ^(2)=0.205,2.257,P>0.05).Conclusion The treatment of dry eye patients with meibomian gland dysfunction by massaging the meibomian glands and taking medicine has obvious therapeutic effect,effectively prolonging the tear film rupture time,reducing the score of self-conscious symptoms,and the clinical effect is significant.