肥大细胞及杯状细胞在肠易激综合征发病机制中的作用

Role of mast cells and goblet cells in the pathogenesis of irritable bowel syndrome

肠易激综合征(IBS)是指一种以腹痛伴排便习惯改变为特征而无器质性病变的常见功能性肠病。IBS发病机制复杂,目前尚未完全阐明。近年来研究发现肥大细胞及杯状细胞与IBS发病机制及临床症状发生密切相关,本文就肥大细胞及杯状细胞在IBS发病机制中的作用做一综述。

Irritable bowel syndrome(IBS)refers to a common functional bowel disease characterized by abdominal pain and changes in bowel habits without organic disease.The pathogenesis of IBS is complex and has not yet been fully elucidated.In recent years,studies have found that mast cells and goblet cells are closely related to the pathogenesis and clinical symptoms of IBS.This article reviews the roles of mast cells and goblet cells in the pathogenesis of IBS.