抗肿瘤药物暴露风险与防范措施

Potential Risk and Prevention of Anti-Tumor Drugs Exposure

抗肿瘤药物在治疗疾病的同时,也可能会对医疗工作者带来健康风险。目前对于抗肿瘤药物暴露防护多针对静脉药物配置中心(pharmacy intravenous admixture services,PIVAS)制定,并未对如护理人员、药物运输人员、口服药物调配人员等相关人员的抗肿瘤药物暴露防护进行要求。因此,大量医务人员可能处于抗肿瘤药物暴露的风险之中。正确理解暴露的风险是加强防护的首要工作。本文拟通过对抗肿瘤药物暴露后危害、防范措施等方面进行综述,特别对非配置环节的防护要求进行了梳理,以期对医务人员抗肿瘤药物暴露的防护提供参考依据。

Anti-tumor drugs may pose health risks to health care workers as well as treating diseases.At present,attentions of anti-tumor drug exposure protection are all focused on pharmacy intravenous admixture services(PIVAS),however,there are little requirements for anti-tumor drug exposure protection for other staffs,e.g.nurses,staffs for transportation,oral drug dispensing and other relevant works.As a result,a large number of medical personnel may be at risk of exposure to anti-tumor drugs.Correct understanding of exposure risks is the primary work of strengthening protection.In this paper,the risk of anti-tumor drug exposure protection,preventive measures and other aspects were reviewed,and in particular,the protection requirements of non-PIVAS environments were summarized,which is intended to provide references for the exposure protection of medical personnel.