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沙库巴曲缬沙坦钠联合替格瑞洛治疗不稳定型心绞痛合并慢性心力衰竭患者的效果 被引量:4

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摘要 目的:观察沙库巴曲缬沙坦钠联合替格瑞洛治疗不稳定型心绞痛合并慢性心力衰竭患者的效果。方法:选取78例不稳定型心绞痛合并慢性心力衰竭患者作为研究对象,按随机数字表法将其分为对照组和观察组各39例。对照组采用替格瑞洛联合氢氯噻嗪片治疗,观察组在对照组基础上加用沙库巴曲缬沙坦钠治疗,比较两组临床疗效、治疗前后心功能指标水平、心绞痛发作次数和心绞痛持续时间,以及不良反应发生率。结果:观察组治疗总有效率为89.74%(35/39),明显高于对照组的66.67%(26/39),差异有统计学意义(P<0.05);观察组左室射血分数和每搏输出量均高于对照组,差异有统计学意义(P<0.05);观察组心绞痛持续时间短于对照组,心绞痛发作次数少于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:沙库巴曲缬沙坦钠联合替格瑞洛和氢氯噻嗪片治疗不稳定型心绞痛合并慢性心力衰竭患者可提高治疗总有效率和心功能指标水平,缩短心绞痛持续时间,以及减少心绞痛发作次数,其效果优于替格瑞洛联合氢氯噻嗪片治疗。
作者 白静
出处 《中国民康医学》 2021年第15期23-25,共3页 Medical Journal of Chinese People’s Health
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