针刺联合拔罐治疗老年肿瘤患者抑郁状态的临床疗效

Clinical study on acupuncture combined with cupping in treatment of tumor-related depression

目的:探讨基于"心脑共主神明"理论采用针刺联合拔罐治疗老年肿瘤抑郁状态的临床疗效。方法:将100例符合纳入标准的患者随机分为观察组(针刺拔罐组)50例、对照组(盐酸帕罗西汀组)50例,均连续治疗4周。应用老年抑郁量表(GDS)和生活质量核心问卷(QLQ-C30问卷)进行评价研究,观察两组疗效并加以比较。结果:治疗后,两组GDS评分均较治疗前明显降低;观察组在轻度抑郁改善方面有明显优势,GDS评分均低于对照组;在中重度抑郁状态方面,两种方法均可降低GDS评分,但差异无统计学意义。两组QLQ-C30问卷比较,治疗前各维度评分比较差异无统计学意义(均P>0.05),具有可比性。治疗前后对比,口服盐酸帕罗西汀后,在疲乏、失眠、食欲减退、呼吸困难方面的评分较治疗前下降(P<0.05),情绪功能、角色功能、社会功能及总体生活质量评分较治疗前有所上升(P<0.05)。经针刺联合拔罐干预,在疲乏、疼痛、恶心呕吐、呼吸困难、失眠、食欲减退、便秘、腹泻方面的症状评分方面,观察组均较治疗前下降(均P<0.05),认知功能、情绪功能、躯体功能及总体生活质量评分均较治疗前上升(均P<0.05);两组治疗后组间比较,除经济困难、角色与社会功能外,观察组其他各项评分均明显改善(均P<0.05)。结论:通过针刺联合拔罐治疗,可明显改善老年肿瘤患者伴发的抑郁状态,提高生活质量。

Objective:To explore the clinical efficacy of acupuncture combined with cupping in the treatment of depression in elderly tumor patients based on the theory of " Heart and brain dominate mental activity". Methods:100 patients who met the inclusion criteria were randomly divided into acupuncture combined cupping group 50 cases,paroxetine hydrochloride tablets group 50 cases,all for 4 weeks of continuous treatment. The Geriatric Depression Scale(GDS)and the core quality of life questionnaire(QLQ-C30 questionnaire)were used for evaluation and study. The therapeutic efficacy of the two groups of patients was observed and compared. Results:After treatment,the GDS scores of the two groups of patients were significantly lower than before treatment;the observation group had a significant advantage in the improvement of mild depression,and the GDS scores were lower than the Western medicine control group;in terms of moderate and severe depression,both methods The GDS score of patients can be reduced,but the difference is not statistically significant. In the QLQ-C30 questionnaire,before and after treatment,the control group’s symptom scores of fatigue,insomnia,loss of appetite,and dyspnea decreased compared with before treatment(P<0.05),emotional function,role function,social function and overall quality of life The score was improved compared with before treatment(P <0.05). The observation group’s symptom scores of fatigue,pain,nausea and vomiting,dyspnea,insomnia,loss of appetite,constipation,and diarrhea decreased compared with before treatment(all P<0.05),cognitive function,emotional function,physical function and overall life The quality scores were improved compared with before treatment(both P<0.05);after treatment,the observation group,except for financial difficulties,roles and social functions,all other scores were significantly improved compared with the control group(all P<0.05). Conclusion:Acupuncture combined with cupping therapy is better than oral paroxetine hydrochloride tablets in the treatment of tumor associated depression,and it can also improve the quality of life of cancer patients.