临床药师参与1例下肢蜂窝组织炎患者伴感染性多器官功能障碍综合征的临床用药分析及药学监护

Analysis on Clinical Pharmacists Participated in Clinical Medication in a Patient of Cellulitis of Lower Extremity with IMODS and Its Pharmaceutical Care

目的:探究临床药师参与下肢蜂窝组织炎患者伴感染性多器官功能障碍综合征(infectious multiple organ dysfunction syndrome,IMODS)的临床用药及其药学监护。方法:临床药师参与1例下肢蜂窝织炎伴感染性多器官功能障碍综合征患者的会诊,并结合患者生理、病理情况、病原菌的培养及抗菌药物的作用特点,提出个体化抗感染治疗方案并实施药学监护。结果:临床医生采纳抗感染治疗方案后,停用头孢替安,改用利奈唑胺,以及加用氟康唑抗真菌感染治疗,症状得以控制,治疗效果较为确切。结论:临床药师参与抗感染用药会诊对促进患者病情改善和抗菌药物合理使用发挥了积极的作用。

Objective:To explore the clinical medication in clinical pharmacists participated in treatment of a patients with cellulitis of lower extremity with infectious multiple organ dysfunction syndrome(IMODS)and its pharmaceutical care.Methods:Clinical pharmacists participated in the consultation of a patient with lower extremity cellulitis with IMODS,and combined with the physiological and pathological conditions of the patient,the culture of pathogenic bacteria and the characteristics of antibacterial drugs action,putting forward to individualize anti-infection medication plan and implemented pharmaceutical care.Results:After the clinicians adopted the anti-infective medication regimen,cefotiam was stopped,linezolid was replaced,and fluconazole was added for anti-fungal infection medication.The symptoms were controlled and therapeutic efficacy was achieved.Conclusion:The participation of clinical pharmacists in the consultation of anti-infective medication plays a positive role in promoting the improvement of patients'condition and rational usage of antibacterials.