难治性肺炎支原体肺炎的预测因素

Predictive factors of refractory Mycoplasma pneumoniae pneumonia

肺炎支原体是引起学龄前和学龄期儿童社区获得性肺炎的常见病因之一。虽然在部分儿童中呈自限性,但仍存在一些病例发展为难治性肺炎支原体肺炎(RMPP),表现为各种肺内及肺外并发症,如支气管黏液栓形成、坏死性肺炎等,甚至危及患儿生命。近年来,随着RMPP的发病率上升,有研究表明尽早使用皮质类固醇治疗能显著改善其临床症状和预后,因此了解肺炎支原体肺炎的致病机制、确定预测RMPP及其相关并发症的高危因素,并制定相关的预测量表就显得尤为重要。

Mycoplasma pneumoniae is one of the common causes of community-acquired pneumonia in preschool and school-age children.Although it is self-limited in some children,there are still some cases of refractory Mycoplasma pneumoniae pneumonia(RMPP),which are characterized by various intrapulmonary and extrapulmonary complications,such as the formation of bronchial mucus plugs,necrotizing pneumonia and so on,and even endanger the lives of children.In recent years,with the increase of morbidity of RMPP,some studies have shown that early use of corticosteroids can significantly relieve its clinical symptoms and improve prognosis.Therefore,it is essential to understand the pathogenesis of Mycoplasma pneumoniae pneumonia,identify the high risk factors for predicting RMPP and its associated complications,and then formulate relevant prediction scales.