脉冲振荡法与呼出气一氧化氮分数测定在特发性肺纤维化中的应用进展

Research progress in the application of impulse oscillometry and fractional exhaled nitric oxide in idiopathic pulmonary fibrosis

脉冲振荡法(IOS)和呼出气一氧化氮分数测定(FeNO)是两种评估肺功能的检测方法,能够提供标准化肺功能测试中没有捕捉到的重要功能信息。这两种方法对于特发性肺纤维化(IPF)都可能是比较有前途的疾病评估和检测工具。因此,将IOS和FeNO方法进行标准化是有必要的。笔者对IOS、FeNO在IPF中应用的研究进展进行综述,同时还探讨了这两种检测手段的局限性及其在IPF中应用的价值。

Impulse oscillometry(IOS)and exhaled nitric oxide fraction determination(FeNO)are two detection methods to evaluate lung function,which can provide important functional information not captured in standardized lung function tests.These two methods may be promising disease assessment and detection tools for idiopathic pulmonary fibrosis(IPF).Therefore,it is necessary to standardize IOS and FeNO methods.This paper reviews the research progress of IOS anti FeNO in IPF,and discusses the limitations of these two detection methods and their application value in IPF.