基于三苯基膦的氨基酸型两性水溶性膦配体的合成及其在1-辛烯氢甲酰化反应中的应用

Synthesis of amino acid type water-soluble phosphine ligand and its application in the hydroformylation of 1-octene

设计合成了几种基于三苯基膦(PPh 3)的氨基酸型两性水溶性膦配体,将其应用于1-辛烯氢甲酰化反应。考察了Rh(acac)(CO)2作为催化剂前体时,配体结构对1-辛烯氢甲酰化反应的影响。研究表明配体结构对催化活性的影响较大,特别是配体的空间位阻效应。

Herein we reported several novel amphoteric water-soluble amino acid modified PPh 3 ligands for hydroformylation of 1-octene.The impact of ligand structures on the Rh-catalyzed hydroformylation of 1-octene had been tested.It was found that ligand structures were vital for the catalytic activity,particularly the spatial baffle effects.