综合护理干预对卵巢癌患者细胞减灭术后腹腔热灌注化疗的影响

Effects of Comprehensive Nursing Intervention on Hyperthermic Intraperitoneal Chemotherapy after Cytoreductive Surgery of Ovarian Cancer Patients

目的:观察综合护理干预对卵巢癌患者细胞减灭术后腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)的影响。方法:选取2016年1月-2020年12月细胞减灭术后第一次行腹腔内热灌注化疗的卵巢癌患者80例,将其随机分为两组,各40例。对照组接受常规护理,观察组在对照组基础上实施综合护理干预。比较两组护理效果。结果:T_(1)时观察组HR、MAP均明显低于对照组,PI明显高于对照组,差异有统计学意义(P<0.05);T_(2)时,两组PI均明显高于T_(1)时,差异有统计学意义(P<0.05);护理后,观察组SAS、SDS评分均明显低于对照组(P<0.05)。护理后观察组躯体功能、心理功能、社会功能、物质生活评分均高于对照组,差异有统计学意义(P<0.05)。观察组护理总满意度为95.0%,显著高于对照组的72.5%,差异有统计学意义(P<0.05)。对照组不良事件发生率为52.5%,高于观察组的25.0%,差异有统计学意义(P<0.05)。结论:卵巢癌患者细胞减灭术后HIPEC期间实施综合护理干预,有助于优化生命体征,缓解负性情绪,降低不良事件发生率,提升患者生活质量,提高护理满意度。

Objective:To observe the effect of comprehensive nursing intervention on hyperthermic intraperitoneal chemotherapy(HIPEC)after cytoreductive surgery of ovarian cancer patients.Method:From January 2016 to December 2020,80 patients with ovarian cancer who underwent HIPEC for the first time after cytoreductive surgery were selected.They were randomly divided into two groups with 40 cases in each group.The control group received routine nursing,and the observation group implemented comprehensive nursing intervention on the basis of the control group.The nursing effect of the two groups was compared.Result:At T1,the HR and MAP in the observation group were significantly lower than those in the control group,and PI was significantly higher than that in the control group,the differences were statistically significant(P<0.05).At T2,the PI was significantly higher than that at T1 in the two groups,the differences were statistically significant(P<0.05).After nursing,the scores of SAS and SDS in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).After nursing,physical function,psychological function,social function,material life score in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The total nursing satisfaction of the observation group was 95.0%,which was significantly higher than 72.5%of the control group,the difference was statistically significant(P<0.05).The incidence of adverse events in the control group was 52.5%,which was higher than 25.0%in the observation group,the difference was statistically significant(P<0.05).Conclusion:Comprehensive nursing intervention in patients with ovarian cancer during HIPEC after cytoreductive surgery is helpful to optimize vital signs,relieve negative emotions,reduce the incidence of adverse events,improve the quality of life of patients and improve nursing satisfaction.