嗜酸性粒细胞计数在变应性鼻炎患儿中的临床意义

The clinical significance of eosinophil count in patients with allergic rhinitis

目的本文旨在探讨外周血嗜酸性粒细胞计数在变应性鼻炎患儿中的临床辅助诊断价值。方法通过回顾性分析方法,收集在广州医科大学附属第一医院确诊的117例变应性鼻炎患儿及118例在广州市越秀区妇幼保健院体检的健康儿童检查结果,并结合变应性鼻炎严重程度,视觉模拟量表结果进行相关性分析。结果变应性鼻炎患儿外周血嗜酸性粒细胞较正常儿童高,嗜酸性粒细胞数与tIgE、打喷嚏、眼痒的症状相关,且不同严重程度变应性鼻炎中嗜酸性粒细胞数与症状相关性存在差异。结论外周血嗜酸性粒细胞计数可以辅助诊断变应性鼻炎,结合tIgE可以反映变应性鼻炎的严重程度。

Objective To investigate the clinical value of peripheral blood eosinophil count in the auxiliary diagnosis of children with allergic rhinitis.Methods 117 children with allergic rhinitis diagnosed in the First Affiliated Hospital of Guangzhou Medical University and 118 healthy children from the physical examination of the Maternal and Children Health Care Hospital in Yuexiu District in Guangzhou were collected through retrospective analysis,and the correlation analysis was conducted based on the resultes ofthe severity of allergic rhinitis and Visual Analog Scale.Results Compared with healthy children,peripheral blood eosinophil count were higher in children with allergic rhinitis.The number of eosinophil in patients with allergic rhinitis was correlated with tIgE、eye itching and sneezing.There was a statistically difference in the correlation between eosinophil count and symptom in different degrees of allergic rhinitis.Conclusions Peripheral blood eosinophil count can assist in the diagnosis of allergic rhinitis,and combined with tIgE can reflect the severity of allergic rhinitis.