双源CT能谱曲线与碘浓度在甲状腺良恶性病变中的应用价值

Application Value Analysis of Dual-source CT Spectrum Curve and Iodine Concentration in Benign and Malignant Thyroid Diseases

目的:探究双源计算机断层扫描(CT)能谱曲线与碘浓度在甲状腺良恶性病变中的应用价值。方法:回顾性选取商丘市第一人民医院2018年1月至2021年1月收治的30例甲状腺癌患者作为甲状腺癌组,选取同期30例结节性甲状腺肿患者作为结节性甲状腺肿组,两组患者均经病理学检查确诊,且接受双源CT检查。比较两组患者平扫时能谱曲线斜率值及碘浓度,动脉期能谱曲线斜率值及甲状腺与颈总动脉碘浓度比值,静脉期能谱曲线斜率值及甲状腺与颈总动脉碘浓度比值情况。结果:经双源CT平扫时,结节性甲状腺肿组患者的能谱曲线斜率值、碘浓度水平均高于甲状腺癌组,差异具有统计学意义(P<0.05);结节性甲状腺肿组患者动脉期的能谱曲线斜率值、甲状腺与颈总动脉碘浓度比值均高于甲状腺癌组患者,差异具有统计学意义(P<0.05);结节性甲状腺肿组患者静脉期的能谱曲线斜率值、甲状腺与颈总动脉碘浓度比值与甲状腺癌组患者相比,差异无统计学意义(P>0.05)。结论:双源CT能谱曲线与碘浓度在甲状腺良恶性病变的诊断中联用,可获得甲状腺癌、结节性甲状腺肿平扫时、动脉期及静脉期的能谱曲线斜率及碘浓度情况,鉴别出患者病情进展情况。

Objective To explore the application value of dual-source computed tomography(CT)energy spectrum curve and iodine concentration in thyroid benign and malignant lesions.Methods A retrospective selection of 30 patients with thyroid cancer admitted to the Shangqiu First People's Hospital from January 2018 to January 2021 was selected as the thyroid cancer group,and 30 patients with nodular goiter during the same period were selected as the nodular goiter group.Both groups were diagnosed by pathological examination and received dual-source CT examination.Compare the slope value of the energy spectrum curve and the iodine concentration,the arterial phase energy spectrum curve slope value and the ratio of thyroid and common carotid artery iodine concentration,the venous phase energy spectrum curve slope value and the ratio of thyroid and common carotid artery iodine concentration.Results After dual-source CT plain scan,the energy spectrum curve slope value and iodine concentration level of the nodular goiter group were higher than those of the thyroid cancer group,the difference was statistically significant(P<0.05);nodular goiter The slope value of the energy spectrum curve in the arterial phase and the ratio of iodine concentration between the thyroid and the common carotid artery of the patients in the thyroid cancer group were higher than those in the thyroid cancer group,and the difference was statistically significant(P<0.05);the energy in the venous phase of the nodular goiter group.There were no statistically significant differences in the slope value of the spectral curve and the ratio of thyroid and common carotid iodine concentration compared with patients in the thyroid cancer group(P>0.05).Conclusion Dual-source CT energy spectrum curve and iodine concentration can effectively diagnose thyroid cancer,nodular goiter,the slope of the energy spectrum curve and iodine concentration during plain scan,arterial phase and venous phase in thyroid benign and malignant lesions,and identify the progress of the disease and have high diagnostic value.