摘要
目的探讨降钙素原联合超敏C反应蛋白检测对小儿肺炎早期诊断的应用价值。方法选取90例小儿肺炎患儿作为观察组,根据实验室检测结果将观察组患儿分为细菌性肺炎组(50例)与非细菌性肺炎组(40例);另选取45例健康体检儿童作为对照组。对比三组儿童的降钙素原及超敏C反应蛋白水平。结果细菌性肺炎组降钙素原、超敏C反应蛋白水平分别为(3.17±0.32)ng/ml、(35.01±7.03)mg/L,均高于非细菌性肺炎组的(0.49±0.13)ng/ml、(12.93±4.71)mg/L及对照组的(0.17±0.04)ng/ml、(5.54±2.11)mg/L,差异有统计学意义(P<0.05);非细菌性肺炎组降钙素原、超敏C反应蛋白水平均高于对照组,差异有统计学意义(P<0.05)。结论降钙素原联合超敏C反应蛋白检测对小儿肺炎早期诊断具有良好的应用价值,对肺炎的鉴别诊断可提供有效帮助,为临床精确治疗有指导作用。
Objective To discuss the practical value of combined detection of procalcitonin and hypersensitive C-reactive protein in early diagnosis of pediatric pneumonia.Methods There were 90 cases of pediatric pneumonia selected as the observation group,and they were divided into bacterial pneumonia group(50 cases)and non-bacterial pneumonia group(40 cases)according to the laboratory test results.Another 45 healthy subjects were selected as the control group.The levels of procalcitonin and high-sensitivity C-reactive protein in the three groups at different periods were compared.Results The levels of procalcitonin and highsensitivity C-reactive protein of bacterial pneumonia group were(3.17±0.32)ng/ml and(35.01±7.03)mg/L,which were obviously higher than(0.49±0.13)ng/ml and(12.93±4.71)mg/L of non-bacterial pneumonia group,and(0.17±0.04)ng/ml and(5.54±2.11)mg/L of the control group.All the difference was statistically significant(P<0.05).The levels of procalcitonin and high-sensitivity C-reactive protein of non-bacterial pneumonia group were higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Combined detection of procalcitonin and hypersensitive C-reactive protein has good practical value in early diagnosis of pediatric pneumonia,and can help the differential diagnosis of pneumonia and provide guidance for clinical accurate treatment.
作者
侯颖
黄靖怡
HOU Ying;HUANG Jing-yi(Dalian Central Hospital,Dalian 116003,China)
出处
《中国实用医药》
2021年第25期26-28,共3页
China Practical Medicine
关键词
降钙素原
超敏C反应蛋白
小儿肺炎
早期诊断
Procalcitonin
Hypersensitive C-reactive protein
Pediatric pneumonia
Early diagnosis