妊娠期糖尿病合并妊娠期高血压疾病孕妇的临床特点分析

Analysis of clinical characteristics of pregnant women with gestational diabetes mellitus and hypertensive disorder complicating pregnancy

目的分析妊娠期糖尿病合并妊娠期高血压疾病孕妇的临床特点。方法选取100例妊娠期糖尿病合并妊娠期高血压疾病孕妇作为实验组,另选同期正常妊娠孕妇100例作为常规组。统计比较两组孕妇临床指标[孕前体质量指数(BMI)≥25 kg/m^(2)、年龄>30岁、孕周、家族病史(糖尿病、高血压)、接受教育年限、孕早期空腹血糖(FPG)≥6.1 mmol/L、初产妇、甘油三酯(TG)>4.73 mmol/L],并进行妊娠期糖尿病合并妊娠期高血压疾病危险因素的Logistic逐步回归分析。结果两组孕妇的接受教育年限、孕周比较,差异无统计学意义(P>0.05);实验组孕妇的孕前BMI≥25 kg/m^(2)、年龄>30岁、家族病史(糖尿病、高血压)、孕早期FPG≥5.1 mmol/L、初产妇、TG>4.73 mmol/L占比分别为65.00%、60.00%、50.00%、40.00%、30.00%、55.00%,均高于常规组的40.00%、40.00%、30.00%、18.00%、15.00%、30.00%,差异具有统计学意义(P<0.05)。Logistic回归分析显示,孕前BMI≥25 kg/m^(2)、年龄>30岁、家族病史(糖尿病、高血压)、初产妇均为妊娠期糖尿病合并妊娠期高血压疾病的危险因素(P<0.05)。结论临床中引起妊娠期糖尿病合并妊娠期高血压疾病的因素较多,需要采取针对性预防措施,整体保障母婴安全。

Objective To analyze the clinical characteristics of pregnant women with gestational diabetes mellitus and hypertensive disorder complicating pregnancy.Methods There were 100 pregnant women with gestational diabetes mellitus and hypertensive disorder complicating pregnancy selected as the experimental group,and another 100 pregnant women with normal pregnancy in the same period as the conventional group.The clinical indicators[pre-pregnancy body mass index(BMI)≥25 kg/m^(2),age>30 years old,gestational week,family medical history(diabetes,hypertension),years of education,fasting plasma glucose(FPG)≥6.1 mmol/L in early pregnancy,primigravida,triglycerides(TG)>4.73 mmol/L]were statistically compared between the two groups,and Logistic regression analysis was used to analyze the risk factors of gestational diabetes mellitus complicated with hypertensive disorder complicating pregnancy.Results There was no statistically significant difference in years of education and gestational weeks between the two groups(P>0.05).The proportions of pregnant women in the experimental group with pre-pregnancy BMI≥25 kg/m^(2),age>30 years old,family medical history(diabetes,hypertension),FPG≥5.1 mmol/L in early pregnancy,primigravida,and TG>4.73 mmol/L were 65.00%,60.00%,50.00%,40.00%,30.00%,and 55.00%,respectively,which were higher than 40.00%,40.00%,30.00%,18.00%,15.00%,and 30.00%in the conventional group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that pre-pregnancy BMI≥25 kg/m^(2),age>30 years old,family medical history(diabetes,hypertension),and primipara were all risk factors for gestational diabetes mellitus complicated with hypertensive disorder complicating pregnancy(P<0.05).Conclusion There are many factors that can cause gestational diabetes mellitus complicated with hypertensive disorder complicating pregnancy in clinical practice,and targeted prevention measures is needed to ensure the safety of mother and infant.