女性缺血性卒中后早期神经功能恶化的危险因素

Risk factors for early neurological deterioration after ischemic stroke in women

目的:缺血性卒中后早期神经功能恶化(END)的发生率为5%~40%,该文旨在评估女性缺血性卒中后END的危险因素。方法:对479例48 h内收住院的缺血性卒中患者,收集吸烟、年龄、血压及维生素D水平等数据,使用SPSS 25.0统计学软件对其进行统计分析。结果:共有136例(28.4%)END患者,平均年龄(64.1±10.256)岁,其中女性72例(52.9%),差异具有显著性。该文单独对女性患者进行分析发现,收缩压、肌肝、吸烟及维生素D缺乏是女性缺血性卒中后END的独立危险因素。结论:收缩压、肌肝、吸烟及维生素D缺乏是女性缺血性卒中后END的独立危险因素。

Objective:The incidence of early neurological deterioration after ischemic stroke is about 5%~40%.This study aims to evaluate the risk factors of END after ischemic stroke in women.Methods:The data of smoking,age,blood pressure and vitamin D level were collected from 479 patients with ischemic stroke admitted to hospital within 48 hours.SPSS25.0 was used for statistical analysis.Results:There were 136(28.4%)END patients,the mean age was(64.1±10.256)years old,among whom 72(52.9%)were females,the difference was significant.In a separate analysis of women,systolic blood pressure,creatinine,smoking,and vitamin D deficiency were independent risk factors for END after female ischemic stroke.Conclusion:Systolic blood pressure,creatinine,smoking and vitamin D deficiency are the END after female ischemic stroke Independent risk factors.