三阴性乳腺癌患者MRI影像学特征与CA153、CEA相关性研究

Correlation between MRI features and CA153 and CEA in patients with triple negative breast cancer

目的:探讨三阴性乳腺癌患者MRI影像学特征与CA153、CEA间相关性。方法:以在某医院接受治疗的109例女性TNBC患者为研究对象,回顾分析患者病例资料,主要包括患者术前MRI检查结果(病灶大小、类型、个数)及实验室检查结果(血清肿瘤标志物CA153、CEA),通过Pearson相关性分析评估连续变量间相关关系。结果:109例患者血清CA153阳性率占42.20%(46例)、CEA阳性占39.45%(43例),且Pearson相关性分析发现病灶大小与血清CA153、CEA存在一定的相关关系(r=0.415/0.258,P<0.05)、CEA(r=0.274/0.169,P<0.05)。结论:TNBC忘者现病灶大小与血清CA153、CEA相关,临床上可结合MRI检查、血清CA153、CEA检测来为TBNC患者提供诊断参考、预后的预测依据。

Objective:To analyze the correlation between MRI imaging features and CA153 and CEA in patients with triple negative breast cancer.Methods:109 female TNBC patients who received treatment in our hospital were selected as the research subjects.The patient case data were retrospectively analyzed,including preoperative MRI examination results(lesion size,type and number)and laboratory examination results(serum tumor markers CA153 and CEA).The correlation between continuous variables was evaluated by Pearson correlation analysis.Results:In 109 patients,the positive rate of serum CA153 was 42.20%(46 cases),and the positive rate of CEA was 39.45%(43 cases).Pearson correlation analysis showed that there was a certain correlation between lesion size and serum CA153 and CEA(r=0.415/0.258.P<0.05),CEA(r=0.274/0.169,P<0.05).Conclusion:The size of lesions in TNBC patients is related to serum CA153 and CEA.In clinical practice,MRI examination,serum CA153 and CEA can be combined to provide diagnostic reference and prognostic basis for TBNC patients.