CT脑灌注成像定量分析在急性脑梗死早期诊断及手术指导中的临床价值研究

Clinical Value of Quantitative Analysis of CT Cerebral Perfusion Imaging in the Early Diagnosis and Treatment of Acute Cerebral Infarction

目的CT脑灌注成像定量分析在急性脑梗死早期诊断及治疗指导中的临床价值进行探讨研究。方法收集在本院2018年6月至2019年6月收治的90例急性脑梗死患者的临床资料。进行CT检查,对患者CT图像进行分析;观察梗死部位及大小情况,并对不同部位CT检查的值比较。结果缺血半暗带区、健侧区、梗死区三者之间CBF、CBV、MTT水平比较差异有统计学意义(P<0.05),健侧区、脑梗区血容量值低于缺血半暗带区(P<0.05)。健侧区CBV水平明显高于缺血区和脑梗区(P<0.05);健侧区MTT水平低于缺血半暗带区和脑梗死区,脑梗死区高于缺血半暗带区,差异有统计学意义(P<0.05)。结论CT灌注成像对直观显示梗死部位病灶大小、位置及缺血半暗带,并能通过区分患者脑组织灌注健侧区、缺血半暗带区、脑梗死区,为临床早期溶栓治疗及手术治疗提供依据。

Objective To explore the clinical value of quantitative analysis of CT cerebral perfusion imaging in the early diagnosis and treatment of acute cerebral infarction.Methods Clinical data of 90 patients with acute cerebral infarction admitted to our hospital from June 2018 to June 2019 were collected.CT examination was performed to analyze the patient's CT image.The location and size of the infarct were observed,and the values of CT examinations for different sites were compared.results There were significant differences in the levels of CbF,CbV,and MTT between the ischemic penumbra,the healthy side,and the infarction zone(P<0.05).The blood volume value in the healthy and cerebral infarction areas was lower than that in the ischemic penumbra(P<0.05).The CbV level in the healthy side was significantly higher than that in the ischemic and cerebral infarction areas(P<0.05).The MTT level in the healthy side was lower than that in the ischemic penumbra and cerebral infarction area.The MTT level in the cerebral infarction area was higher than that in the ischemic penumbra area,and the difference was statistically significant(P<0.05).Conclusion CT perfusion imaging can visually show the size,location,and ischemic penumbra of the infarct site,and can provide a basis for early clinical thrombolytic therapy and surgical treatment by distinguishing the perfusion healthy side area,ischemic penumbra area,and cerebral infarction area of the patient's brain tissue.