探讨周围型肺癌MSCT影像学表现与临床组织病理学的相关性研究

Correlation between Imaging Features of MSCT and Clinical Histopathology of Peripheral Lung Cancer

目的旨在探讨周围型肺癌多层螺旋CT(MSCT)影像学表现与临床组织病理学的相关性。方法回顾性分析2017年12月至2019年1月于我院就诊治疗的68例周围型肺癌患者的临床、影像学资料,以术后病理活检检查结果为标准,分析MSCT检查征象与病理学检查中病灶与组织病理类型之间的关系。结果不同组织病理类型周围型肺癌患者其病灶部位分布及直径大小比较均无差异(P>0.05);空泡征、毛刺征、磨玻璃征、胸膜凹陷征及空气支气管征在腺癌中的发生率显著高于鳞癌和大细胞和小细胞癌患者,而钙化佂、分叶征、空洞形成和支气管血管集束征发生率在腺癌和鳞癌中比较无差异(P>0.05);不同组织病理类型周围型肺患者其平扫CT值、增强60s后CT值比较差异间均无统计学意义(P>0.05)。结论不同组织病理类型的周围型肺癌患者其病灶部位分布、大小以及CT扫描中平扫、强化CT值无明显差异,但不同病理类型患者中其相关CT征象存在差异,故掌握好MSCT在周围型肺癌中的特征表现对其病理类型的鉴别诊断具有重要意义。

Objective To investigate the correlation between imaging features of multi-slice spiral CT(MSCT)and clinical histopathology of peripheral lung cancer.Methods The clinical and imaging data of 68 patients with peripheral lung cancer who were treated in our hospital from December 2017 to January 2019 were retrospectively analyzed.The results of postoperative pathological biopsy were used as the standard to analyze the relationship between MSCT examination signs and lesions and pathological types in pathological examination.Results There was no difference in the distribution of lesions and diameter between patients with different histopathological types of peripheral lung cancer(P>0.05).The incidence of vocule sign,burrs sign,ground-glass opacity,pleural indentation and air bronchograms in patients with adenocarcinoma was significantly higher than that in patients with squamous carcinoma and large cell and small cell carcinoma,but there was no difference in the incidence of calcified sign,lobulated sign,porosis and Bronchovascular cluster sign between adenocarcinoma and squamous carcinoma(P>0.05).There were no significant differences in the CT values of plain scan and the CT values in 60 s atfer enhancement and the difference between the two between the patients with different histopathological types(P>0.05).Conclusion There were no significant differences in the distribution and size of lesions and the plain and enhanced CT values in CT scans between patients with different histopathological types of peripheral lung cancer.However,there were differences in CT signs between patients with different pathological types.Therefore,mastering the characteristics of MSCT in peripheral lung cancer is of great significance for the differential diagnosis of the pathological types.