3.0T MRI多b值DWI与动态增强扫描对前列腺癌术前诊断价值

Preoperative Diagnostic Value of Multiple b-value DWI of 3.0T MRI and Dynamic Contrast Enhancement Scanning for Prostate Cancer

目的分析3.0T磁共振(MRI)多b值弥散加权成像(DWI)与动态增强(DCE)扫描对前列腺癌术前诊断价值。方法选取本院2017年4月至2019年11月收治的82例穿刺活检疑似前列腺癌的患者作为研究对象,分析DCE-MRI与DWI检查诊断前列腺癌的敏感性、特异性、准确性,比较前列腺癌与前列腺增生不同b值的ADC值。结果以病理学活检为“金标准”,DCE-MRI联合DWI检查诊断前列腺癌的敏感性、特异性、准确性分别为93.33%、89.19%、91.46%,其敏感性与病理学比较无差异(P>0.05);前列腺癌不同b值的ADC值均小于前列腺增生,两者比较差异显著(P<0.05)。结论3.0T MRI多b值DWI与DCE-MRI在诊断前列腺癌中具有一定的临床应用价值,术前可有效鉴别诊断前列腺良恶性疾病,具有较高的诊断准确性。

Objective To analyze the preoperative diagnostic value of multiple b-value diffusion-weighted imaging(DWI)of 3.0 T magnetic resonance imaging(MRI)and dynamic contrast enhancement(DCE)scanning for prostate cancer.Methods 82 patients with suspected prostate cancer treated with puncture biopsies in our hospital from April 2017 to November 2019 were selected as the research objects.The sensitivity,specificity,and accuracy of DCE-MRI and DWI in the diagnosis of prostate cancer were analyzed.The ADC values of different b-values in prostate cancer and prostate hyperplasia were compared.Results Pathological biopsy was used as the gold standard.The sensitivity,specificity,and accuracy of DCE-MRI combined with DWI in the diagnosis of prostate cancer were 93.33%,89.19%,and 91.46%,respectively.There was no difference in sensitivity compared with pathology(P>0.05).The ADC values of different b values of prostate cancer were lower than those of benign prostatic hyperplasia,and the difference was significant(P<0.05).Conclusion Multi-b-value DWI and DCEMRI of 3.0 T MRI have some clinical application value in diagnosing prostate cancer.It can effectively distinguish and diagnose benign and malignant prostate diseases before surgery and has higher diagnostic accuracy.