开展中医药比较效益研究思路及方法探讨

Discussion on Ideas and Methods of Comparative Benefit Research of Traditional Chinese Medicine

比较效益研究通过比较不同干预措施或策略带来的实际效益,为临床决策和卫生政策的制定提供有效信息。开展中医药比较效益研究,应基于循证医学、真实世界研究、大数据研究等理念,采取效力研究与效果研究结合、主动评价与被动监测结合等方式,采用真实世界的前瞻性研究设计或回顾性数据分析,医院集中监测的注册登记式研究设计,网状Meta的复杂多干预措施疗效分析方法,医院HIS系统大数据挖掘,药物经济学评价方法,综合评价不同中医药干预措施的受益及风险。

Comparative benefit study provides effective information for clinical decision-making and health policy-making by comparing the actual benefits brought by different intervention measures or strategies.The comparative benefit research of traditional Chinese medicine should be based on the concepts of evidence-based medicine,real-world research and big data research,adopt the combination of effectiveness research and effect research,active evaluation and passive monitoring,adopt the real-world prospective research design or retrospective data analysis,and the registered research design of centralized hospital monitoring,The complex multi intervention efficacy analysis method of mesh Meta,big data mining of hospital HIS system and pharmacoeconomic evaluation method comprehensively evaluate the benefits and risks of different traditional Chinese medicine interventions.