严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)眼表感染研究进展

Research progress of severe acute respiratory syndrome coronavirus 2 in ocular surface infection

严重急性呼吸综合征冠状病毒2型(SARS-CoV-2,又称COVID-19)经眼表传播远较经口鼻传播困难,然而现有证据认为眼表传播仍是一条可能的途径,尤其对于医护人员。本文描述了SARS-CoV-2相关的眼表症状,阐释了眼表SARS-CoV-2入胞的可能机制和与眼表相关的SARS-CoV-2传播机制,并对现有的和未来可能的研究方向进行了剖析,为从眼表考虑临床治疗SARS-CoV-2提供新的思路与方法,帮助人们研发出更多的治疗策略。

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),also known as COVID-19,is much more difficult to transmit through the ocular surface than that through the mouth and nose.However,the available evidence has suggested the possibility of ocular surface transmission,especially in medical staff.In this paper,we describe the existing SARS-CoV-2 ocular surface symptoms,the possible mechanism of SARS-COV-2 entering ocular surface cells and SARS-COV-2 transmission through ocular surface.In addition,the existing and future possible research directions of SARS-CoV-2 transmission through ocular surface were analyzed,so as to provide new ideas and methods for clinical treatment of SARS-CoV-2 from the perspective of ocular surface.