菘蓝属植物化学成分及药理作用研究进展

Research Progress on Chemical Constituents and Pharmacological Effects of Isatis

菘蓝属植物在中国药用历史悠久,其中菘蓝的根和叶即为板蓝根和大青叶。该属植物化学成分多样,主要包括生物碱类、硫代葡萄糖苷类、木脂素类、黄酮类等,具有抗菌、抗病毒、抗内毒素、抗肿瘤、抗炎、免疫增强等药理作用。本文对近40年来国内外有关菘蓝属植物化学成分和药理作用的文献进行系统的总结,为该属植物的进一步研究开发提供参考。

Isatis has a long history of medicinal use in China,among which the roots and leaves of Isatis indigotica are Banlangen and Daqingye.Genus Isatis plants have a variety of chemical constituents,including alkaloids,glucosinolates,lignans and flavonoids,which have the pharmacological activities of antibacterial,antivirus,antiendotoxin,antitumor,anti-inflammatory,immune regulation,etc.The paper made a systematic summary about research on the chemical constituents and pharmacological effects of Isatis in China and abroad for forty years to provide the references for further studies.