摘要
将从未经处理大鼠体内分离出来的肝微粒体与蛋白合成能量系统,同位素标记氨基酸以及各种浓度镉、铅、汞在体外一起温育以测定镉、铅、汞对氨基酸掺入微粒体蛋白中的影响.实验结果表明,上述三种金属都抑制氨基酸向肝微粒体蛋白中的掺入.随着这些金属在体外浓度的增加,此种抑制作用,也越明显.
Hepatic microsomes from untreated rats, energy system of protein synthesis, labelled amino acids and cadmium, lead and mercury respectively, were incubated in vitro to observe the effects of these metals on ami-no acid incorporation into microsomal protein. The results showed that the amino acid incorporation could be inhibited by all three metals with dose-effect dependence.
出处
《环境科学学报》
CAS
CSSCI
CSCD
北大核心
1989年第2期204-207,共4页
Acta Scientiae Circumstantiae
关键词
氨基酸
微粒体
蛋白
镉
铅
汞
cadmium
mercury
lead
amino acid incorporation
mi-crosome.