远志属植物化学成分及其药理活性研究进展

Study Progress on Chemical Constituents and Biological Activities of Polygala Genus

远志科远志属植物全世界约有500种,天然分布于欧亚大陆、美洲的温带和亚热带地区,我国有50种,主产于西南和华南等省区。研究发现远志属植物主要含有皂苷类、酮类、寡糖酯类等成分,药理研究表明其具有抗抑郁、抗炎、抗肿瘤、抗衰老、益智等药理活性。文章对近十年来国内外远志属植物的化学成分及药理活性研究进展进行了系统的概述总结和展望。

The plants of the Polygala L.genus(Polygalaceae family),comprising about 500 species worldwide,are mainly distributed in temperate regions and subtropics of Eurasia and America.About 50 species of this genus can be found in southwestern and southern part of China.Previous studies have demonstrated the main components of this genus plants including saponins,xanthones,oligosaccharides and so on.Pharmacological studies have shown that crude extracts or pure compounds from Polygala have anti-depression,anti-inflammatory,anti-tumor,anti-aging,mental and other pharmacological activities.This paper systematically summarizes and prospects the research progress on the chemical constituents and pharmacological activities of Polygala genus over the past decade,in order to provide scientific basis and reference for the development of Polygala genus.