对原发性肝癌从脾胃论治“调护中洲”的理论基础与临床意义的研讨

Theoretical basis and clinical significance of treating primary liver cancer from the perspective of“regulating and protecting Zhongzhou”in the spleen and stomach

就原发性肝癌(PLC)从脾胃论治“调护中洲”治法的理论基础与临床价值进行了分析讨论,认为PLC的发生发展与多种因素导致“中洲”脾胃受损相关,“中洲不顾”脾胃运化失常是PLC重要的病理机制,健脾和胃、“顾护中洲”是扶正抗癌的重要举措。并通过现代文献研究结果,分析阐述了调理脾胃复方及相关辨病中药在提高机体免疫、抑制肿瘤细胞增殖等方面的抗癌药理作用;通过临床研究结果,佐证了健脾和胃“顾护中洲”治法方药对PLC的客观疗效和优势。最终认为,在PLC的辨治过程中,重视脾胃后天之本,“顾护中洲”,采用健脾益气、健脾和胃类方药,将有助于整体临床疗效的提高。

This article analyzes and discusses the theoretical basis and clinical significance of the treatment of primary liver cancer(PLC)from the perspective of“regulating and protecting Zhongzhou”in the spleen and stomach.The development and progression of PLC is associated with the damage of“Zhongzhou”in the spleen and stomach caused by various factors,and“ignoring Zhongzhou”and dysfunction of spleen and stomach are the important pathological mechanism of PLC,while strengthening the spleen and stomach and“caring for Zhongzhou”are important measures to strengthen vital Qi and fight against cancer.With reference to the research findings of modern studies,this article elaborates on the antitumor pharmacological effect of compound spleen/stomach-regulating prescription and related traditional Chinese medicine(TCM)drugs in improving immunity and inhibiting tumor cell proliferation,and clinical research findings further confirm the objective therapeutic efficacy and advantages of TCM drugs and prescriptions for strengthening the spleen and stomach and“caring for Zhongzhou”in the treatment of PLC.It is believed that during the syndrome differentiation and treatment of PLC,the acquired foundation of the spleen and stomach should be taken seriously,and it is necessary to“take care of Zhongzhou”and apply TCM drugs and prescriptions for strengthening the spleen,benefiting Qi,and strengthening the spleen and stomach,so as to improve overall clinical outcome.