单孔腹腔镜手术治疗卵巢囊肿的临床疗效及安全性分析

Clinical efficacy and safety analysis of laparoendoscopic single-site surgery for treating ovarian cyst

目的探讨单孔腹腔镜手术治疗卵巢囊肿的临床疗效和安全性。方法回顾性分析接受腹腔镜手术治疗的62例卵巢囊肿患者的临床资料,根据手术方法将患者分为观察组(31例)和对照组(31例)。对照组应用传统三孔腹腔镜手术治疗,观察组予以单孔腹腔镜手术治疗。观察两组患者术中失血量、手术时间、住院时间、术后24 h最高体温等围术期情况,生殖激素指标水平,治疗效果,并发症发生率,以及血清炎症因子水平。结果观察组的术中失血量少于对照组,手术时间、住院时间短于对照组,术后24 h最高体温低于对照组(均P<0.05);观察组治疗总有效率明显高于对照组,并发症发生率显著低于对照组(均P<0.05);治疗后观察组白细胞介素-8(IL-8)、白细胞介素-6(IL-6)以及肿瘤坏死因子-α(TNF-α)水平均明显低于对照组(均P<0.05);治疗前后两组促卵泡激素(FSH)、促黄体生成素(LH)、雌二醇(E 2)水平差异均无统计学意义(均P>0.05)。结论对卵巢囊肿患者采取单孔腹腔镜手术治疗效果显著,可有效缩短手术时间与住院时间,降低炎症因子水平,减少并发症发生,提高临床治疗的安全性和可靠性。

Objective To investigate the clinical efficacy and safety of laparoendoscopic single-site surgery in the treatment of ovarian cyst.Methods The clinical data of 62 patients with ovarian cyst received laparoscopic surgery for treatment were retrospectively analyzed.According to the surgical methods,the patients were divided into observation group(31 cases)and control group(31 cases).The conventional laparoendoscopic three-site surgery was employed in the control group,whereas the observation group received laparoendoscopic single-site surgery for treatment.The perioperative indicators including intraoperative bleeding volume,surgery duration,hospitalization duration,and highest body temperature 24 hours after surgery,as well as the reproductive hormone indicators levels,therapeutic effects,incidence of complications,and serum inflammatory factors levels were observed in both groups.Results The observation group yielded less intraoperative bleeding volume,shorter duration of surgery and hospitalization,and a lower highest body temperature 24 hours after surgery as compared with the control group(all P<0.05).Compared to the control group,the observation group yielded higher total effective rate,whereas lower incidence of complications(all P<0.05).After treatment,the patients in the observation group obtained lower levels of interleukin-8(IL-8),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)in the comparison of the control group(all P<0.05).There were no statistically significant differences in the levels of follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E 2)between the two groups before and after treatment(all P>0.05).Conclusion Employing laparoendoscopic single-site surgery on patients with ovarian cyst has prominent therapeutic effects,which can effectively shorten the duration of surgery and hospitalization,decrease inflammatory factors levels,reduce the prevalence of complications,and improve the safety and reliability of clinical treatment.