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去乙酰毛花苷注射液在婴幼儿心力衰竭治疗中的应用现状 被引量:2

Application Status of Cedilanide in Treatment of Infantile Heart Failure
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摘要 去乙酰毛花苷注射液(商品名西地兰)在婴幼儿心力衰竭治疗中主要发挥正性肌力作用,并可通过负性频率作用、神经内分泌作用等对心力衰竭的治疗产生积极作用。西地兰作为有效的强心剂,在婴幼儿心力衰竭治疗中具有特殊地位,但也存在一定局限性,如其沉积可能引起心律失常加重等,且其应用安全性有待提升。目前,关于西地兰与其他药物联合治疗婴幼儿心力衰竭的研究仍处于初级阶段,但对指导未来婴幼儿心力衰竭的治疗具有积极意义,可能成为未来婴幼儿心力衰竭治疗的新方向。 Cedilanid has a positive inotropic effect in the treatment of infantile heart failure, which can also play a positive role in the treatment of heart failure through negative frequency effects, and neuroendocrine effects.At present, as an effective cardiotonic agent, cedilanid has a special position in the treatment of infantile heart failure, but it also has certain limitations, such as the presence of deposits, which may cause the arrhythmia to worsen, while its safety also needs to be improved.At present, although studies using other drugs in combination with cedilanid for the treatment of infantile heart failure are in the initial research stage, they have a positive significance in guiding the treatment of such diseases in the future, and may become the new direction for the treatment of infantile heart failure in the future.
作者 董鑫 栾俊锐 DONG Xin;LUAN Junrui(Department of Pharmacy,Qingdao Traditional Chinese Medicine Hospital/Hiser Medical Center of Qingdao,Qingdao 266000,China;Department of Pharmacy,Qingdao Massage Rehabilitation Hospital,Qingdao 266000,China)
出处 《医学综述》 CAS 2021年第17期3493-3497,共5页 Medical Recapitulate
关键词 心力衰竭 婴幼儿 去乙酰毛花苷注射液 Heart failure Infants and young children Cedilanid
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