烧伤灶感染病原菌及其耐药性随住院时间变迁的研究进展

Research progress in burn infection pathogens and drug resistance with the length of stay during hospitalization

随着医疗水平的不断进步,烧伤患者可以获得及时的医疗救治、更多的液体复苏和足够的营养支持,急性期烧伤患者的病死率明显降低。但是,由于烧伤患者皮肤屏障功能被破坏,感染成为烧伤患者住院期间死亡的最主要原因。对于烧伤患者总体的病原菌及其耐药性的研究已经不能满足临床的需求。文章就近年来关于烧伤灶感染病原菌及其耐药性随住院时间(LOS)的变迁进行综述,旨在指导临床更有针对性和更有效地使用抗菌药物。

With the continuous development of medical standards,burn patients can get timely medical treatment,and more fluid resuscitation and sufficient nutrients reduce the mortality of patients in acute stage.However,because of the destruction of skin barrier of burn patients,infection has become the main cause of death of burn patients during hospitalization.The researches on the overall pathogens and drug resistance of burn patients have not been able to meet the needs of clinicians.This review focuses on the changes in burn infection pathogens and drug resistance with the length of stay(LOS)in the recent years,in order to provide the methods for effective antibiotic use for clinic.