新型天然活性物修护肌肤机理分析

Analysis of mechanism of new natural product in repairing skin

简要介绍了皮肤羰基化反应的诱因,重点从皮肤中蛋白质羰基化产生机理分析了其对人体肌肤产生的不良反应。讨论了蛋白质的降解系统,最后根据蛋白质的羰基化产生机理以及降解方式,提出建议解决方案:二葡糖基棓酸、玫瑰茄花提取物、欧洲酸樱桃花提取物可以通过降低ROS含量和三角褐指藻提取物提高20S酶体活性加速羰基化蛋白质水解水平降低人体肌肤蛋白质羰基化水平,实现对肌肤的完美修护。

The inducement of skin carbonylation was briefly introduced.The mechanism of protein carbonylation from skin was discussed and the adverse reactions to human skin were analyzed.According to the mechanism of protein carbonylation and the degradation mode,the proposed solutions are as follows:Diglucosyl gallic acid,Hibiscus sabdariffa flower extract and Prunus cerasus flower extract can reduce the protein carbonylation level of human skin by reducing the content of ROS;Phaeodactylum tricornutum extract can improve the activity of 20S enzyme.Therefore,the hydrolysis level of carbonylated protein will be accelerated to achieve the perfect repair of skin.