室性早搏的中医证候研究述评

Research Review on TCM Syndromes of Premature Ventricular Complexes

室性早搏(以下简称室早)中医证候分布受患者地域、年龄、性别、Myerbury危险度分级、合并其他疾病情况的影响,且与自主神经功能变化、血液流变学指标及窦率震荡指标的变化存在相关性。目前,室早的中医证候研究仍处于初级阶段,缺乏定量化的证候诊断标准,室早表观遗传学与证候相关性研究仍是空白,故今后需进一步加强室早定性化的辨证分型、定量化的证候诊断、规范化的中医药证治用药研究,尽早建立室早的诊断标准及诊断量表,在此基础上开展针对我国不同地区室早患者的大样本、多中心的证候分布研究;进一步开展室早证候的生物标志物研究,以明确其证候标志物,在中医药证治方面构建从分子生物学到生物学基础、证候诊断与治疗的完整体系。

The distribution of TCM syndromes of premature ventricular complexes(PVCs)is affected by the patient′s region,age,gender,Myerbury risk classification,and the impact of other diseases.And it is correlated with changes in autonomic nerve function,blood rheology indexes,and sinus rate oscillating indexes.At present,the research on TCM syndromes in PVCs is still in its infancy,and there is a lack of quantitative diagnostic criteria for its syndromes.And research on the correlation between PVCs epigenetics and syndromes has always been barren.Therefore,in the future,it is necessary to further strengthen the qualitative syndrome differentiation,quantitative diagnosis of syndromes,and standardized TCM treatment and medication research,and establish laboratory diagnostic criteria and diagnostic scales as soon as possible.On basis of which,carry out a large sample,multi-center syndrome distribution study for PVCs patients in different regions of our country,and launch research on the PVCs biomarkers to clarify its syndrome markers,and construct a complete system from molecular biology to biological basis,syndrome diagnosis and treatment in the aspect of TCM syndrome.