期刊文献+

甘精胰岛素治疗糖尿病的不良反应分析 被引量:1

下载PDF
导出
摘要 目的:探索甘精胰岛素治疗糖尿病的不良反应。方法:选择60例糖尿病患者为试验对象,根据单双号随机化分组,各30例,分别选择常规降糖治疗、胰岛素治疗。结果:观察组FBG(5.09±0.15)mmol/L、HbA1C(6.21±0.39)%、2hPBG(7.13±0.27)mmol/L、HOMA-β(174.28±15.03)、HOMA-IR(1.19±0.45)、不良反应发生率(3.33%)均优于对照组(P<0.05)。结论:对糖尿病患者实施胰岛素治疗效果显著,可降低不良反应。
作者 许兰 马源
出处 《北方药学》 2021年第4期150-151,共2页 Journal of North Pharmacy
  • 相关文献

二级参考文献40

  • 1吴泰相,刘关键.隐蔽分组(分配隐藏)和盲法的概念、实施与报告[J].中国循证医学杂志,2007,7(3):222-225. 被引量:174
  • 2United Kingdom Prospective Diabetes Study(UKPDS). 13:Relative efficacy of randomly allocated diet, sulphonylurea. insulin, or metfannin in patients with newly diagnosed non-insulin dependent diabetes followed for three years. BMJ, 1995,310: 83-88.
  • 3Kahn SE, Haffner SM, Heise MA, et al. Glycemic durability of rosiglitazone , metformin , or glyburide monotherapy. N Engl J Med, 2006,355: 2427-2443.
  • 4Brown JB, Conner C, Nichols GA Secondary failure of metfonnin monotherapy in clincal practice. Diabetes Care, 2010, 33 : 501-506.
  • 5Cook MN, Ginnan CJ ,Stein pp, et al. Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes. Diabetes Care, 2005,28: 995-1000.
  • 6Bunck MC, Diamant M, Corner A, et al. One-year treatment with exenatide improves beta-cell function, compared with insulin glargine , in metfonnin-treated type 2 diabetes patients: a randomized, controlled trial. Diabetes Care, 2009 ,32: 762-768.
  • 7Diamant M, Van Gaal L,Stranks Svet al. Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes C DURATION-3) : an open-label randomized rial. Lancet,2010,375:2234-2243.
  • 8Diamant M, Van Gaal L,Stranks Svet al. Safety and efficacy of once-weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks. Diabetes Care,2012,35 , 683-689.
  • 9Russell-Jones 0, Vaag As Schmitz 0, et al. Liraglutide vs insulin glargine and placebo in combination with metfonnin and sulfonylurea therapy in type 2 diabetes mellitusCLEAD-5 met+ SU): a randomized controlled trial. Diabetologia, 2009, 52: 2046-2055.
  • 10Heine RJ, Van Gaal LF,Johns D,et al. Exenatide versus insulin glargine inpatients with suboptimally controlled type 2 diabetes- a randomized trial. Ann Inter Med,2005, 143: 559-569.

共引文献5157

同被引文献5

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部