宽肠活血汤对术后炎性肠梗阻患者术后恢复及并发症的影响

Efficacy of the Kuanchang Huoxue decoction on postoperative recovery and complications of patients with postoperative inflammatory bowel obstruction

目的:观察宽肠活血汤对术后炎性肠梗阻患者术后恢复及并发症的影响,以指导未来肠梗阻治疗方案优化。方法:选取术后炎性肠梗阻患者146例,随机分为2组,各73例。对照组予以常规治疗,观察组予以宽肠活血汤治疗,比较两组临床疗效、术后恢复情况、并发症发生率及生活质量。结果:观察组整体治疗效果优于对照组,总有效率较对照组高,差异有统计学意义(P<0.05);两组治疗10 d中医证候积分均较治疗前降低,且观察组低于对照组,差异有统计学意义(P<0.05);治疗期间,观察组肛门排气时间、自觉症状改善时间及排便时间均较对照组低,腹围减少尺寸较高,差异有统计学意义(P<0.05);两组治疗10 d血清白细胞介素-6、肿瘤坏死因子-α、C反应蛋白水平均较治疗前降低,且观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05);相较于治疗前,两组治疗10 d后躯体、环境、心理、综合及社会各维度评分均升高,且观察组较对照组高,差异有统计学意义(P<0.05)。结论:对术后炎性肠梗阻患者采用宽肠活血汤治疗可促进患者术后恢复,缓解临床症状,降低并发症发生率,提高临床治疗效果,调节炎症因子水平,改善患者生活质量,值得临床推广应用。

Objective:To observe the effect of the Kuanchang Huoxue decoction(宽肠活血汤)on postoperative recovery and complications of patients with postoperative inflammatory bowel obstruction,so as to guide the optimization of future intestinal obstruction treatment plans.Methods:146 patients with postoperative inflammatory bowel obstruction were selected and randomly divided into 2 groups,with 73 cases in each group.The control group was given conventional treatment,and the observation group was given the Kuanchang Huoxue decoction.The clinical efficacy,postoperative recovery,complication rate and quality of life were compared between the two groups were be compared.Results:The overall treatment effect of the observation group was better than that in the control group,and the total effective rate was higher than that in the control group.The difference was statistically significant(P<0.05),the scores of TCM syndromes of both groups were lower than before treatment for 10 days,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).During the treatment period,the observation group’s anal exhaust time,self-conscious symptom improvement time,and defecation time were lower than those of the control group,and the size of the abdominal circumference was higher,and the difference was statistically significant(P<0.05).The levels of serum interleukin-6,tumor necrosis factor-α,and C-reactive protein in the two groups were lower than before treatment for 10 days,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Compared with before treatment,the scores of the physical,environmental,psychological,comprehensive and social dimensions of the two groups increased after 10 days of treatment.And the observation group was higher than the control group,the difference was statistically significant(P<0.05).Conclusion:Treatment of patients with postoperative inflammatory bowel obstruction with the Kuanchang Huoxue decoction can promote postoperative recovery,relieve clinical symptoms,reduce the incidence of complications,improve clinical treatment effects,adjust the level of inflammatory factors,and improve the quality of life of patients.It is worthy of clinical practice promote applications.