重复经颅磁刺激联合深呼吸体操对卒中后抑郁患者情绪和功能康复的影响

Effect of repetitive transcranial magnetic stimulation combined with deep breathing gymnastics on emotional and functional rehabilitation of patients with post-stroke depression

目的:观察重复经颅磁刺激(rTMS)联合深呼吸体操对卒中后抑郁(PSD)患者情绪和功能康复的影响。方法:50例PSD患者随机分为观察组和对照组各25例,2组患者均给予常规的康复训练,对照组在此基础上给予空白磁刺激联合深呼吸体操,观察组在此基础上给予rTMS刺激联合深呼吸体操。分别于治疗前和治疗4周后,采用24项汉密尔顿抑郁量表(HAMD-24)﹑改良Barthel指数(MBI)以及脑卒中专用生活质量量表(SS-QOL)对2组患者进行评估。结果:治疗4周后,2组患者HAMD-24评分较治疗前均明显降低(均P<0.05),且观察组更低于对照组(P<0.05);MBI、SS-QOL各项目评分及总分较治疗前均明显升高(均P<0.05),且观察组以上评分更高于对照组(P<0.05)。结论:rTMS联合深呼吸体操能进一步缓解PSD患者的抑郁情绪,并改善患者的日常生活活动能力以及生活质量,该联合治疗模式值得在PSD患者中应用推广。

Objective:To observe the effect of repetitive transcranial magnetic stimulation(rTMS)combined with deep breathing gymnastics on emotional and functional rehabilitation of patients with post-stroke depression(PSD).Methods:Totally,50 cases of PSD were randomly divided into treatment group and control group,25 cases in each group.All patients were given routine rehabilitation training,the control group was given blank magnetic stimulation and deep breathing gymnastics,and the treatment group was given rTMS stimulation and deep breathing gymnastics.Before and 4 weeks after treatment,24-Item Hamilton Depression Scale(HAMD-24),Modified Barthel Index(MBI)and Stroke Special Quality of Life Scale(SS-QOL)were used to evaluate the two groups.Results:After 4 weeks of treatment,the HAMD-24 score in the two groups was significantly lower than that before treatment(both P<0.05),and that in the treatment group was significantly lower than that in the control group(P<0.05).MBI score,SS-QOL scores and total scores were significantly higher after treatment than those before treatment(all P<0.05),and the average scores in the treatment group were significantly higher than those in the control group(all P<0.05).Conclusion:rTMS combined with deep breathing gymnastics can further alleviate the depression of PSD patients,and improve their activities of daily living ability and quality of life.The combined treatment mode is worthy of application and promotion in PSD patients.