基于CiteSpace软件的奥司他韦安全性研究可视化分析

Visual analysis on Oseltamivir safety studies using CiteSpace software

目的通过分析现有奥司他韦安全性的研究文献,了解该领域的研究现状及热点,为后续研究提供参考。方法以Web of Science为检索平台,检索时间为建库至2020年2月1日,纳入与奥司他韦安全性相关的文献,利用检索平台提供的文献分析功能,结合CiteSpace 5.6.R3软件对奥司他韦安全性的相关文献进行分析。结果共纳入国外文献390篇,国际上与奥司他韦安全性相关的文献起步于1999年,年度发文量的变化与流行性感冒流行趋势一致。国际学者之间合作少,尚未形成密切的合作网络。发文量前10位的机构以企业为主,研究机构间的合作主要为企业联合高校。国际上专门针对奥司他韦安全性的研究较少,多数研究是在有效性研究的基础上开展的,收集的安全性信息有限。结论奥司他韦的安全性研究仍处于初期阶段,需要继续通过上市后监测不断累积更多的信息。

Objective This study aimed to analyze the safety research status and hotspots of Oseltamivir,and to provide ideas for further studys.Methods Using Web of Science as the retrieval platform,the retrieval time is from the establishment of the database to February 1,2020,the literatures related to Oseltamivir security were included and analyzed with CiteSpace 5.6.R3 software.Results A total of 390 international literatures were included.International literatures related to the safety of Oseltamivir started in 1999,and changes in annual publications were consistent with the trend of influenza.There was little cooperation between international scholars and a close cooperation network had not been formed.Top 10 institutions were mainly enterprises,and the cooperation among research institutions was mainly enterprise joint universities.There were few studies on the safety of Oseltamivir in the world,most of which were based on the effectiveness study,and the safety information was limited.Conclusion Safety studies of Oseltamivir are still in their early stages and more information will continue to accumulate through post-market surveillance.