维生素D对多囊卵巢综合征患者生育影响的研究进展

Effect of vitamin D on patients with polycystic ovary syndrome

多囊卵巢综合征(PCOS)是常见的妇科内分泌疾病,常见临床表现包括月经不规律、高雄激素血症、胰岛素抵抗及排卵障碍性不孕等。目前关于PCOS的确切病因与发病机制尚不清楚。研究发现PCOS患者普遍存在维生素D的缺乏,适当补充维生素D可能有助于改善PCOS患者的临床相关症状及生育情况。本文就目前维生素D对PCOS患者影响的相关文献进行综述。

Polycystic ovary syndrome(PCOS)is a common gynecological endocrine disorder,with clinical manifestations of irregular menses,hyperandrogenaemia or excess levels of androgen,insulin resistance,anovulatory infertility,etc.At present,the exact etiology and pathogenesis of PCOS is still unclear.Studies have found that vitamin D deficiency is common in PCOS,and appropriate vitamin D supplementation may help improve clinically relevant symptoms and fertility status in patients with PCOS.This article reviews the current literature on the influence of vitamin D on PCOS patients.