睾丸支持细胞瘤二例并文献复习

Sertoli cell tumor of testis:two cases report and literature review

目的探讨睾丸支持细胞瘤患者的临床诊疗特点及预后。方法对2例睾丸支持细胞瘤患者临床资料进行回顾性分析,并结合相关文献讨论。结果本文纳入的2例患者均行睾丸根治性切除术,并经术后病理诊断为睾丸支持细胞瘤。第1例患者因术后10个月出现腹膜后淋巴结转移,行腹膜后淋巴结清扫术及术后辅助放疗,并于睾丸切除术后22个月死于肺转移。第2例患者术后未行放、化疗,随访87个月无肿瘤复发或转移。结论睾丸支持细胞瘤术前明确诊断较困难,建议行睾丸根治性切除术,术后出现转移可诊断为恶性,预后较差,术后应定期随访。

Objective To investigate the clinical features and prognosis of Sertoli cell tumor of testis.Methods The clinical data of 2 patients with Sertoli cell tumor of testis were retrospectively analyzed and discussed with related literature.Results Two patients were treated with radical orchiectomy and were diagnosed as Sertoli cell tumor by postoperative pathology.The first patient underwent retroperitoneal lymph node dissection and postoperative radiotherapy because of retroperitoneal lymph node metastasis 10 months after operation.He died of lung metastasis 22 months after orchiectomy.The second patient did not receive radiotherapy or chemotherapy after operation,and no tumor recurrence or metastasis was found after 87 months of follow-up.Conclusion Sertoli cell tumor of testis is difficult to make a definite diagnosis before operation.Radical orchiectomy is recommended.Postoperative metastasis can be diagnosed as malignant with poor prognosis.Regular follow-up after operation is required.