男性和女性类风湿关节炎患者的并发疾病与治疗状况分析

Analysis of Concurrent Diseases and Treatment of Male and Female Rheumatoid Arthritis Patients

目的探讨分析男性和女性类风湿关节炎患者的并发疾病与治疗状况。方法随机选取2017年5月—2019年5月于我院治疗的类风湿关节炎患者205例,分为男性组(71例)和女性组(134例),对两组患者的一般资料、血清学指标、并发疾病和治疗状况进行分析。结果女性类风湿关节炎的发病率高于男性;两组患者的ESR、CRP、RF、抗CCP抗体、SCR的异常率,差异有统计学意义(P<0.05);在<60岁阶段,骨关节炎、糖尿病、高脂血症的发病率男性组略高于女性组,,高血压、骨质疏松的发病率是女性组略高于男性组,差异不具有统计学意义(P>0.05),在≥60岁阶段,高血压、糖尿病的发病率男性组略高于女性组,差异不具有统计学意义(P>0.05);男性患者对于来氟米特的使用率略高于于女性患者,而女性患者对于甲氨蝶呤、羟氯喹、白芍总苷及糖皮质激素的使用率相略高于男性患者,但差异不具有统计学意义(P>0.05)。结论男性和女性类风湿关节炎患者的并发疾病与治疗状况不完全相同,要针对不同性别选择合适的治疗。

Objective To investigate and analyze the complications and treatment status of male and female patients with rheumatoid arthritis.Methods A random selection of 205 patients with rheumatoid arthritis who were treated in our hospital from May 2017to May 2019 were divided into a male group(71 cases)and a female group(134 cases).The general information and serology of the two groups of patients analysis of indicators,concurrent diseases and treatment status.Results The incidence of rheumatoid arthritis is higher than that of men;the abnormal rates of ESR,CRP,RF,anti-CCP antibody,and SCR between the two groups are statistically significant(P<0.05);at the age of<60 years,bone and joint the incidence of inflammation,diabetes,and hyperlipidemia was slightly higher in the male group than in the female group,and the incidence of hypertension and osteoporosis was slightly higher in the female group than in the male group.The difference was not statistically significant(P>0.05).At the age of≥60 years,the incidence of hypertension and diabetes in the male group was slightly higher than that in the female group,and the difference was not statistically significant(P>0.05);the use rate of leflunomide in male patients was slightly higher than that in female patients.The use rate of methotrexate,hydroxychloroquine,total glucocorticoids and glucocorticoids in female patients was slightly higher than that in male patients,but the difference was not statistically significant(P>0.05).Conclusion Male and female patients with rheumatoid arthritis have different concurrent diseases and treatment conditions,and appropriate treatments should be selected for different genders.