白细胞介素基因多态性与布鲁菌病易感性的关系

Relationship between interleukin gene polymorphism and susceptibility to brucellosis

布鲁菌病是一种动物疫源性疾病,可经过皮肤及黏膜、消化道、呼吸道等途径传染给人类。近年来,布鲁菌病发病率有增高趋势,发病机制较为复杂,除细菌、毒素等因素外,遗传易感性逐渐引起广泛重视,本文回顾了既往的相关报道,对白细胞介素基因多态性与布鲁菌病易感性的关系进行综述。

Brucellosis is a kind of animal epidemic disease that can be transmitted to human beings through skin,mucous membrane,digestive tract,respiratory tract and other ways.In recent years,the incidence of brucellosis has increased.Its pathogenesis is relatively complicated.In addition to bacteria,toxins and other factors,genetic susceptibility has gradually attracted the attention of scholars.In this paper,we summarized the previous reports and reviewed the relationship between interleukin gene polymorphism and susceptibility to brucellosis.