摘要
Main observation and conclusion Transition-metal-catalyzed C-H insertion of metal-carbene represents an excellent and powerful approach for C-H functionalization.However,despite remarkable advances in metal-carbene chemistry,transition metal catalysts that are capable of enantioselective intermolecular carbene C-H insertion are mainly constrained to dirhodium(Ⅱ)and iridium(Ⅲ)-based complexes.
基金
Financial support from the National Natural Science Foundation of China(Nos.21971103,21672229)
the National Science&Technology Major Project"Key New Drug Creation and Manufacturing Pro-gram",China(No.2018ZX09711002-006)
the Guangdong Provincial Key Laboratory of Catalysis(No.2020B121201002)is gratefully acknowledged.
