七氟醚潮气量法吸入用于小儿全身麻醉诱导的效果观察

Effect of sevoflurane inhaled by tidal volume method on induction of general anesthesia in children

目的探讨七氟醚潮气量法吸入用于小儿全身麻醉诱导的效果。方法抽取2018年12月至2020年12月与商丘市中心医院行择期腹股沟疝修复术100例患儿,根据随机数字表法分为对照组与研究组,每组50例。全部患儿术中均采用气管插管全身麻醉,对照组经七氟醚肺活量法吸入全身麻醉诱导,研究组经七氟醚潮气量法吸入全身麻醉诱导。比较两组麻醉诱导前(T0)、牵拉疝囊时(T1)、牵拉疝囊后5 min(T2)呼吸循环情况包括舒张压(DBP)、收缩压(SBP)、呼吸频率(RR)、心率(HR)及伤害性刺激反应包括外周灌注指数(PI)所受影响,并比较两组麻醉指标(恢复自主呼吸时间、拔管时间、麻醉诱导时间、苏醒时间)及不良反应发生情况。结果围术期各时点,两组呼吸循环相关指标水平组间、组内比较,差异未见统计学意义(P>0.05);T1、T2时点,对照组PI水平低于研究组,差异有统计学意义(P<0.05);研究组恢复自主呼吸时间、拔管时间、麻醉诱导时间、苏醒时间短于对照组,差异有统计学意义(P<0.05)。两组麻醉后均未见明显不良反应发生。结论小儿全身麻醉经七氟醚潮气量法吸入麻醉诱导,不会对患儿呼吸循环产生明显影响,利于减轻围术期伤害性刺激,患儿自主呼吸时间、拔管时间缩短,无明显不良反应发生。

Objective To analyze the effect of sevoflurane inhaled by tidal volume method on induction of general anesthesia in children.Methods A total of 100 children with inguinal hernia repair from December 2018 to December 2020 were selected.According to the random digital table method,they were divided into control group and research group,50 cases in each group.All children were intubated with general anesthesia.The control group was induced by sevoflurane inhaled by vital capacity method,and the study group was induced by sevoflurane inhaled by tidal volume method.The respiratory and circulatory conditions including diastolic blood pressure(DBP),systolic blood pressure(SBP),respiratory rate(RR),heart rate(HR)and noxious stimulus response including peripheral perfusion index(PI)were compared between the two groups before anesthesia induction(T0),during hernia sac traction(T1)and 5 min after hernia sac traction(T2).The anesthesia indexes(recovery of spontaneous breathing time,extubation time,anesthesia induction time,recovery time)and adverse reactions were compared between the two groups.Results There was no significant difference in the level of respiratory and circulatory indexes between the two groups(P>0.05);at T1 and T2,the PI level of the control group was lower than that of the study group(P<0.05);the recovery time of spontaneous breathing,extubation time,anesthesia induction time and awakening time of the study group were shorter than those of the control group(P<0.05).There was no obvious adverse reaction in the two groups after anesthesia.Conclusions Anesthesia induction by sevoflurane inhaled by tidal volume method in children's general anesthesia has no obvious effect on the respiratory circulation of children,which is conducive to reducing the perioperative noxious stimulation,shortening the spontaneous breathing time and extubation time of children,and no obvious adverse reactions.