基于国医大师周仲瑛临证医案的交泰丸集内关联解析

In-set Association Analysis of Jiaotai Pills Based on the Clinical Cases of ZHOU Zhongying,Master of Traditional Chinese Medicine

目的:总结周仲瑛教授运用交泰丸的经验。方法:采用Medcase Ver 3.8采集医师工作室医案,建构交泰丸数据库,使用集内关联数据挖掘方法,进行医案解构分析。结果:本次研究病例158诊次,病机138条,药物234种。数据产生高关联症状为失眠、口干、怕冷、便溏;高关联舌象为苔淡黄、苔黄、质暗、质暗紫、质红;高关联脉象为滑脉、小脉、数脉、弦脉;高关联病机为湿阻气滞、肝肾不足、湿浊中阻、胆胃不和;高关联药物为黄连、肉桂、川芎、丹参、知母、炒酸枣仁、法半夏、炙甘草。结论:周仲瑛教授运用交泰丸治疗者症状多表现为失眠、口干、怕冷、便溏,病机虚实夹杂、寒热错杂,病理因素以痰、湿、热为主,治疗常配伍川芎、丹参、知母、炒酸枣仁、法半夏、炙甘草等。

Objective:To summarize Professor ZHOU Zhongying’s experience in using Jiaotai Pills.Methods:Medcase Ver 3.8 was used to collect medical records from the physician’s studio and construct the Jiaotai Pills database.In-set association data mining method was utilized to conduct deconstruction analysis of the medical records.Results:In this study,there were 158 consultations,138 pathogeneses,and 234 types of medicines.Highly correlated symptoms were insomnia,dry mouth,aversion to cold,and loose stools.Highly correlated tongue conditions were light yellow or yellow tongue coating,dark,dark purple or red tongue texure.Highly correlated pulse conditions were slippery pulse,small pulse,rapid pulse and wiry pulse.High-associated pathogeneses included dampness obstruction and qi stagnation,liver and kidney deficiency,dampness turbidity retention in middle energizer,gallbladder-stomach disharmony.High-associated medicines were Huanglian(Coptidis Rhizoma),Rougui(Cinnamomi Cortex),Chuanxiong(Chuanxiong Rhizoma),Danshen(Salviae miltiorrhizae Radix et Rhizoma),Zhimu(Anemarrhenae Rhizoma),Shuzaoren(Ziziphi Spinosae Semen),Fabanxia(Pinelliae Rhizoma Praeparatum),Zhigancao(Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle).Conclusions:Professor ZHOU Zhongying applied Jiaotai Pills mostly in symptoms of insomnia,dry mouth,aversion to cold and loose stools.The pathogeneses were mixed with deficiency and excess,and cold-heat complex.The pathological factors were mainly phlegm,dampness,and heat.The treatment was often compatible with Chuanxiong,Danshen,Zhimu,Shuzaoren,Fabanxia,Zhigancao,etc.