血管内介入治疗急性缺血性卒中临床效果评价

Evaluation of Clinical Effect of Intravascular Interventional Treatment of Acute Ischemic Stroke

目的探讨对于急性缺血性卒中患者应用血管内介入治疗的临床疗效。方法抽取2016年3月-2020年11月该院68例急性缺血性卒中患者,依据治疗方案分组,观察组患者以血管内介入治疗,对照组运用静脉溶栓治疗,对比两组患者的血管再通率、神经功能、预后评分及血清Hcy、Fib水平在治疗前后的变化。结果治疗10 d后观察组的NIHSS评分(6.06±0.25)分,低于对照组的(8.19±1.15)分,差异有统计学意义(t=10.553,P<0.001);观察组GOS评分(4.59±0.32)分,高于对照组(4.23±0.26)分,差异有统计学意义(t=5.091,P<0.001);观察组的血管完全再通率97.06%,显著高于对照组76.47%,差异有统计学意义(χ^(2)=4.610,P<0.001);治疗10 d后观察组的血清Hcy(14.02±3.02)μmol/L,对照组(16.59±4.15)μmol/L,差异有统计学意义(t=2.920,P=0.005);观察组Fib(3.06±1.05)g/L,对照组(4.31±1.53)g/L,差异有统计学意义(t=3.928,P<0.001)。结论在急性缺血性卒中患者治疗中采用血管内介入治疗可获得满意疗效,有利于改善其神经功能缺损并提升预后,且有利于提升患者的血管完全再通率并帮助降低血清Hcy及Fib水平,该治疗技术值得在急性缺血性卒中患者的治疗中加以应用并推广。

Objective To explore the clinical efficacy of intravascular interventional therapy for patients with acute ischemic stroke.Methods A total of 68 patients with acute ischemic stroke in the hospital from March 2016 to November 2020 were selected and grouped according to the treatment plan.Patients in the observation group received intravascular interventional therapy,and the control group received intravenous thrombolytic therapy.Changes in vascular recanalization rate,neurological function,prognostic score,and serum Hcy and Fib levels before and after treatment were compared.Results After 10 days of treatment,the NIHSS score of the observation group was(6.06±0.25)points,which was lower than the(8.19±1.15)points of the control group,the difference was statistically significant(t=10.553,P<0.001);and the GOS score of the observation group was(4.59±0.32)points,which was higher than the control group(4.23±0.26)points,the difference was statistically significant(t=5.091,P<0.001);the complete recanalization rate of the observation group was 97.06%,which was significantly higher than the control group 76.47%,the difference was statistically significant(χ^(2)=4.610,P<0.001);Serum Hcy in the observation group(14.02±3.02)μmol/L after treatment for 10 days,and in the control group(16.59±4.15)μmol/L,the difference was statistically significant(t=2.920,P=0.005);observation group of Fib(3.06±1.05)g/L,control group(4.31±1.53)g/L,the difference was statistically significant(t=3.928,P<0.001).Conclusion In the treatment of patients with acute ischemic stroke,endovascular interventional therapy can achieve satisfactory results,which is beneficial to improve the neurological deficit and improve the prognosis,and is beneficial to increase the patient's complete vascular recanalization rate and help reduce serum Hcy and Fib level,this treatment technique is worthy of being applied and promoted in the treatment of patients with acute ischemic stroke.