刘建和运用温胆汤加减治疗高血压病经验浅析

Analysis of LIU Jianhes Experience on Treating Hypertension with Wendan Decoction(温胆汤)

刘建和教授以温胆汤方证病机与高血压病病机均为痰浊湿热、温胆汤主治病证与高血压病病症密切交合为切入点,认为温胆汤可通过畅中化痰、和胃利胆、清热燥湿之功用,来分消痰浊湿热之邪,使高血压病诸症皆除;并结合温胆汤的现代药理研究,认为其主要通过抑制肾素-血管紧张素-醛固酮系统(RASS)激活、利尿、抑制交感兴奋、保护血管内皮功能等机制来有效控制并降低血压。在临床常常以此为指导灵活运用温胆汤进行加减来防治高血压病,获效颇佳。

Professor LIU Jianhe takesthe pathogenesis of Wendan Decoction(温胆汤) and the pathogenesis of hypertension are both phlegm-turbidity and dampness-heat, and the syndrome treated by Wendan Decoction is closely related to the symptoms of hypertension as the entry point.It is believed that Wendan Decoction can eliminate the phlegm-turbidity and dampness-heat by removing phlegm and relaxing the middle, harmonizing stomach andbile-draining, and clearing heat and drying dampness, so as to eliminate all the symptoms of hypertension. From the perspective of modern medicine, Wendan Decoction can effectively control and lower blood pressure by inhibiting the activation of renin-angiotensin-aldosterone system(RASS), diuresis, inhibiting sympathetic excitationand protecting vascular endothelial function. Using this theory as a guide and using the soup flexibly to prevent and treat hypertension, the effect is quite remarkable.