经鼻持续气道正压通气对重型新生儿肺炎治疗效果的影响分析

Effect of nasal continuous positive airway pressure on severe neonatal pneumonia

目的:探讨经鼻持续气道正压通气(NCPAP)应用于重型新生儿肺炎治疗中的效果。方法:2016年1月-2020年11月收治重型新生儿肺炎患儿80例,随机分为两组,各40例。对照组给予鼻导管或头罩吸氧;研究组给予NCPAP。比较两组治疗效果。结果:研究组治疗24 h后的心率及呼吸频率均低于对照组,危重症评分高于对照组,差异有统计学意义(P<0.05);研究组治疗24 h后的PaO2及HCO3水平均高于对照组,PaCO2水平低于对照组,差异有统计学意义(P<0.05);研究组治愈率高于对照组,差异有统计学意义(P<0.05)。结论:NCPAP有利于改善重症新生儿肺炎患儿的临床表现,改善低氧血症,对提升临床治愈率具有积极意义。

Objective:To investigate the effect of nasal continuous positive airway pressure(NCPAP)in the treatment of severe neonatal pneumonia.Methods:From January 2016 to November 2020,80 children with severe neonatal pneumonia were selected and randomly divided into two groups with 40 cases in each group.The control group was given nasal catheter or head mask oxygen inhalation.The study group was given NCPAP.We compared the treatment effect of the two groups.Results:After 24 hours of treatment,the heart rate and respiratory rate of the study group were lower than those of the control group,and the critical illness score was higher than that of the control group,the difference was statistically significant(P<0.05).In the study group,after 24 hours of treatment,PaO2 and HCO3 were higher than those in the control group,PaCO2 was lower than that in the control group,the difference was statistically significant(P<0.05).The cure rate of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:NCPAP is helpful to improve the clinical manifestations of severe neonatal pneumonia,improve hypoxemia,and has positive significance to improve the clinical cure rate.