睑板腺按摩与抗生素滴眼液治疗睑板腺功能障碍性干眼的疗效研究

Effect of eyelid gland massage and antibiotic eye drops on the treatment of eyelid gland dysfunction dry eye

目的探究睑板腺按摩与抗生素滴眼液治疗睑板腺功能障碍性干眼的疗效。方法选取2019年3月至2020年5月本院收治的100例睑板腺功能障碍性干眼患者作为观察对象,随机分为对照组与研究组,每组50例。对照组采用常规抗生素滴眼液(左氧氟沙星眼液+玻璃酸钠眼液)治疗,研究组在对照组基础上采用睑板腺按摩治疗,比较两组临床疗效、治疗前后泪膜破裂时间(BUT)、泪液分泌试验(SIT)及症状评分。结果治疗后,研究组临床总有效率为98.00%,明显高于对照组的82.00%(P<0.05);治疗后,两组BUT、SIT均高于治疗前,且研究组高于对照组(P<0.05);研究组自觉症状、睑板开口状态和脂质性状评分均明显低于对照组(P<0.05)。结论在睑板腺功能障碍性干眼中实施睑板腺按摩治疗,能有效提升临床疗效,延长患者的泪膜破裂时间,增加泪液分泌,并缓解其干眼症状。

Objective To investigate the effect of eyelid gland massage and antibiotic eye drops on the treatment of eyelid gland dysfunction dry eye.Methods 100 patients with eyelid gland dysfunction dry eyesfrom March 2019 to May 2020 were selected as study subjects,and they were randomly divided into control group and study group,with 50 cases in each group.The control group was treated with conventional antibiotic eye drops(levofloxacin eye solution+sodium glassy eye solution).The study group was treated with eyelid gland massage on the basis of the control group.The clinical efficacy,tear film rupture time(BUT),tear secretion test(SIT)and symptom score were compared between the two groups before and after treatment.Results After treatment,the total clinical effective rate of the study group was 98.00%,which was significantly higher than82.00%of the control group(P<0.05);after treatment,the BUT and SIT of the two groups were higher than before treatment,and the study group were higher than the control group(P<0.05).The scores of self-conscious symptoms,tarsal opening state and lipid traits in the study group were significantly lower than those in the control group(P<0.05).Conclusion Eyelid gland massage in dry eyes with eyelid gland dysfunction can effectively improve the clinical efficacy,prolong the tear film rupture time,increase tear secretion,and relieve the symptoms of dry eyes.