胺碘酮治疗急性心肌梗死后室性心律失常的临床价值分析

Clinical value analysis of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction

目的探究胺碘酮治疗急性心肌梗死后室性心律失常的临床效果。方法选取2018年3月至2019年3月本院收治的100例急性心肌梗死后室性心律失常患者作为研究对象,按随机数表法分为对照组和观察组,每组50例。对照组采用利多卡因进行治疗,观察组采用胺碘酮进行治疗,比较两组治疗前后患者心率(HR)、QTC周期、QTd数值,左室舒张末期容积(LVEDV)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)改善情况。结果与治疗前比较,两组治疗后HR、QTd数值降低,QTC周期延长,LVESD值、LVEDV值降低,LVEF值升高,且观察组改善程度均优于对照组,差异有统计学意义(P<0.05)。结论采用胺碘酮治疗急性心肌梗死后室性心律失常患者,能有效改善患者心功能,促进患者心律恢复,具有较高的临床应用价值。

Objective To explore the clinical effect of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction.Methods 100 patients with ventricular arrhythmia after acute myocardial infarction who were admitted to our hospital from March 2018 to March2019 were selected as the research subjects.According to the random number table,they were divided into control group and observation group,with50 cases in each group.The control group was treated with lidocaine,and the observation group was treated with amiodarone.The improvement of heart rate(HR),QTC cycle,QTd value,left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic diameter(LVESD)and left ventricular ejection fraction(LVEF)were compared between the two groups before and after treatment.Results Compared with before treatment,HR and QTd values decreased,QTC cycle prolonged,LVESD value,LVEDV value decreased,and LVEF value increased in the two groups after treatment,and the improvement degree of the observation group was better than that of the control group,the difference was statistically significant(P<0.05).Conclusion The use of amiodarone in the treatment of patients with ventricular arrhythmia after acute myocardial infarction can effectively improve the patient’s heart function and promote the recovery of the patient’s heart rhythm.It has high clinical application value.