薄氏腹针辅助治疗类风湿关节炎及对ESR、RF及CRP水平的影响

Effect of Bo’s abdominal acupuncture as adjunctive therapy on rheumatoid arthritis and ESR,RF and CRP levels

目的:探讨薄氏腹针"引气归元"加"腹四关"治疗类风湿关节炎的疗效及相关作用机制。方法:将104例类风湿关节炎患者随机分为观察组(52例,脱落1例)和对照组(52例,脱落3例)。对照组口服甲氨蝶呤片治疗,每次5 mg,每周1次;观察组在对照组的基础上配合薄氏腹针疗法,穴取中脘、下脘、关元、气海、滑肉门、外陵等,隔日1次,每周3次,两组均治疗12周。观察两组患者治疗前后中医症状评分(包括关节疼痛、关节活动、关节肿胀、晨僵情况),以及血沉(ESR)、类风湿因子(RF)、C反应蛋白(CRP)水平,并评定两组临床疗效。结果:治疗后观察组总有效率为88.2%(45/51),高于对照组的73.5%(36/49,P<0.05)。两组患者治疗后中医症状各项评分及总分均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。两组患者治疗后ESR、RF、CRP水平均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。结论:薄氏腹针"引气归元"加"腹四关"辅助治疗类风湿关节炎能有效改善患者临床症状,其机制与降低ESR、RF及CRP水平有关。

Objective To explore the therapeutic effect on rheumatoid arthritis treated with Bo’s abdominal acupuncture for"guiding qi to the source"plus"opening four gates on the abdomen"and the relevant effect mechanism.Methods A total of 104 patients with rheumatoid arthritis were randomized into and an observation group(52 cases,1 case dropped off)and a control group(52 cases,3 cases dropped off).In the control group,methotrexate tablets were prescribed for oral administration,5 mg each time,once a week.In the observation group,on the base of the treatment as the control group,Bo’s abdominal acupuncture was combined.The acupoints included Zhongwan(CV 12),Xiawan(CV 10),Guanyuan(CV 4),Qihai(CV 6),Huaroumen(ST 24),Wailing(ST 26),etc.The treatment was given once every two days,3 times weekly.Totally 12 weeks were required in the two groups.Before and after treatment,the score of TCM symptoms(including joint pain,the range of motion,joint swelling and morning stiffness),and the levels of erythrocyte sedimentation rate(ESR),rheumatoid factor(RF)and C-reactive protein(CRP)were observed and the clinical therapeutic effect was assessed in the two groups.Results After treatment,the total effective rate was 88.2%(45/51)in the observation group,higher than 73.5%(36/49)in the control group(P<0.05).The score of each TCM symptom and the total scores after treatment were all lower than those before treatment in the two groups(P<0.05),and these scores in the observation group were lower than the control group(P<0.05).After treatment,the levels of ESR,RF and CRP were all lower than those before treatment in the two groups(P<0.05),while the levels of those indexes in the observation group were lower than the control group(P<0.05).Conclusion Bo’s abdominal acupuncture for"guiding qi to the source"plus"opening four gates on the abdomen"as the adjunctive therapy effectively relieves the clinical symptoms in the patients with rheumatoid arthritis,which is related to the reduction of ESR,RF and CRP in mechanism.